Serena and Venus Williams will go head-to-head for the 30th time on Friday after booking their spots in the third round of the US Open.

A potential clash between the sisters was the main talking point after the draw last week and neither looked like wobbling on Tuesday, with Venus defeating Camila Giorgi 6-4 7-5 before Serena saw off Carina Witthoeft 6-2 6-2 in the night session.

It will be the 16th time Venus and Serena have met at a slam, but the earliest stage of a tournament since their very first match in the second round of the Australian Open 20 years ago.

Their last slam clash was in the final of the Australian Open in 2017, when Serena was in the early stages of pregnancy with daughter Olympia.

Venus said: “The last time we played at the Australian Open it was two against one, so at least this time it will be fair.”

Venus won their most recent meeting at Indian Wells in March during Serena’s first tournament back, but the 36-year-old showed how much sharper she has got since then.